Synthesis of texaphyrin conjugates*

نویسندگان

  • Darren J. Magda
  • Zhong Wang
  • Nikolay Gerasimchuk
  • Wenhao Wei
  • Pavel Anzenbacher
  • Jonathan L. Sessler
چکیده

This paper summarizes recent synthetic efforts devoted to the generation of new, second-generation texaphyrin-type drugs, specifically species that involve known or potential anticancer agents covalently attached to a tumor-localizing texaphyrin core. Particular emphasis will be placed on the strategies needed to prepare such systems, as well as on the choice of active group being subject to attachment.

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تاریخ انتشار 2004